According to a 2011 report by the American Society of Clinical Oncology, “fast weight loss,” as defined by 2.8% weight loss at 4 weeks and 5% weight loss at 6 months, was the most common definition of treatment-resistant type 3 diabetes.
A recent study also found that patients who met clinical criteria for treatment resistant type 3 diabetes were more likely to fail to lose weight on average than patients who met criteria for treatment responsive type 3 Diabetes.
How fast do treatment-resistant type 3 Diabetes patients lose weight?
The study found that patients who met treatment-resistant, or treatment responsive, type 3 diabetes were at an even greater risk for weight loss if they lost weight less rapidly than the type 1 or type 2 diabetic patients. However, there was no difference in the mean weight loss among the treatment-resistant type 3 diabetes patients, despite the fact that those who met the above study thresholds all lost equal amounts of weight.
What is considered treatment-resistant type 3 Diabetes?
The definition of treatment-resistant type 1 diabetes is less clear – although most recent research suggests that a patient who meets the diagnosis has a low risk for being treated insensitively with insulin or to continue treatment with insulin. There are, of course, other clinical criteria which allow for more rapid treatment of type 1 or type 2 diabetes, such as the presence of type 2 or severe insulin resistance.
What about treatment responsive type 3 diabetes?
Type 1 Type 2 Type 3 Type 4 Diabetes Treatment Resistant (T1R)
(n = 11) Treatment Responsive (T2R)
(n = 20) 1-6 % 6-12 % 6-12 % 6-12 % 5-12 % Weight loss (lb) 26 31 32 35 40 44 50
(n = 14) (n = 14) (n = 21) (n = 20) (n = 20) Weight gain (g) 18-21 23-28 32-41 37-51 44-55 46-58 51-61 59-64
(n = 13) (n = 15) (n = 18) (n = 15) (n = 16) Mean weight loss (lb) −0.25 −0.29 −0.34 −0.37 −0.38 −0.36 0.01 0.03 0.03 Weight gain (g) −0.03 −0.06 −0.05 −0
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